GST 2420: Atoms and Stars:
An Historical Introduction to Astronomy, Physics, and Scientific
Discovery.
Fall 2002, Section 983, Call Number 16050
Agenda 8 for 10/23
Secondary outcomes incidental to the main focus of a study have less value - example of study to find relationship between pancreatic cancer and smoking found effect due to coffee, which eventually proved to be untrue. Size of population and time span also a factor, with different effects for different types of studies. You might also want to consider who paid for study, did the experimenters or sponsors have control, were there conflicts of interest, was there independent evaluation? A related indicator of quality is independent confirmation. Finally, one study bringing about a major change in treatment or prevention is rare.
The termination of the large double-blind hormone replacement therapy experiment has further resulted in the termination of a related study on a specific population, and researchers are considering terminating a third.